The diversified role of mitochondria in ferroptosis in cancer
Abstract Ferroptosis is a form of regulated cell death induced by iron-dependent lipid peroxidation, and it has been studied extensively since its discovery in 2012.Induced by iron overload and ROS accumulation, ferroptosis is modulated by various cellular metabolic and signaling pathways.The GSH-GPX4 pathway, the FSP1-CoQ10 pathway, the GCH1-BH4 p